Some officials have left their jobs in the wake of Sue Gray's Partygate inquiry, the UK's top civil servant has said.
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Simon Case, the Cabinet Secretary, told MPs "a number of people" had resigned, with a disciplinary process over Covid rule-breaking ongoing.
He revealed civil servants were being encouraged to say if they had been fined during the police inquiry into lockdown parties.
But they would not have to, he added.
The report by senior official Sue Gray, published last month, highlighted breaches of Covid rules in and around Downing Street during lockdown.
The Metropolitan Police issued fines to 83 people, including PM Boris Johnson, his wife Carrie and Chancellor Rishi Sunak, after a separate probe.
Giving evidence to MPs on the Public Administration and Constitutional Affairs Committee, Mr Case said some aspects of Ms Gray's report "would be horrifying in any setting".
"Mistakes were made. Boundaries weren't observed," he added.
He told the MPs he was not involved in the disciplinary process himself, and he could not comment on individual cases because it was confidential.
However, he said the civil service wanted the probe to conclude within weeks, adding: "There's a huge level of uncertainty hanging over individuals who are a part of this".
He added that officials were being encouraged to be "open and honest" about whether they had been fined - but would not be required to be so.
Asked by an MP on the committee whether anyone had offered to resign, Mr Case replied: "Yes".