Three people were killed in a Russian long-range missile attack on the central Ukrainian city of Dnipro on Friday evening.
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Local officials said the missiles hit a factory which makes space rockets and satellites, as well as a nearby street.
Russia's defence ministry said the factory made parts for Ukrainian missiles.
Dnipro has taken in large numbers of Ukrainians fleeing the fighting further east, where Russia has concentrated its forces.
One resident, Klavdia, said a rocket landed just in front of her window.
"It's difficult to understand where to seek shelter during attacks like this. In the basement, behind walls - everything collapses anyway," she told Reuters news agency.
While Russia's ground offensive in the Donbas region of east Ukraine has slowed down, there has been an increase in the number of attacks from the air - often hitting city centres.
On Thursday, 24 people were killed in a Russian missile attack on the city of Vinnytsia, which lies west of Kyiv - a long way from the front lines in the east and south.